An International Ki67 Reproducibility Study
نویسندگان
چکیده
منابع مشابه
An international Ki67 reproducibility study.
BACKGROUND In breast cancer, immunohistochemical assessment of proliferation using the marker Ki67 has potential use in both research and clinical management. However, lack of consistency across laboratories has limited Ki67's value. A working group was assembled to devise a strategy to harmonize Ki67 analysis and increase scoring concordance. Toward that goal, we conducted a Ki67 reproducibili...
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BACKGROUND Ki67 labeling index (LI) is used as a predictive marker and is associated with prognosis in breast cancer. However, standardised methodologies for measurement are lacking which has limited its application in clinical practice. In this study, we evaluated the interobserver concordance of visual assessment of Ki67 LI in breast cancer. METHODS Ki67-immunostained slides of 160 cases of...
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ژورنال
عنوان ژورنال: JNCI: Journal of the National Cancer Institute
سال: 2013
ISSN: 1460-2105,0027-8874
DOI: 10.1093/jnci/djt306